So, let's trace Susan's lineage.
First off, I will cover her paternal lineage in future posts. For now, I will just say that her father was Rodolph Ambrose Spencer, son of Ambrose Spencer and Mercy Ann Russell.
Susan's mother, Telitha Humphries, was born to James Humphries and Sarah Morgan in St. Clair, Alabama.
Telitha had two half siblings from her father's first marriage to Susannah Watkins - Martha and Pinckney. She had two older brothers - John and Uriah - and one younger sister - Louisa Catherine.
There are several databases on Ancestry that confirm the marriage date of 19 May 1841 in St. Clair County, Alabama for James and Sarah. The 1850 U.S. Federal Census has the couple living in St. Clair with children Martha, Pinckney, John, Uriah, and Telitha.
I saved the post above as a draft, because I ran into a few "head scratching" contradictions for some of Telitha's family members. A few databases claim that James had several children with Susannah. For now, though, I will leave Martha and Pickney as is because they are the only ones I can verify.
However, the 1840 Federal Census does report that their were 5 males and 3 females under the age of nineteen living in the home of James. This was one year before he married Telitha's mother, Sarah Morgan, so it is probable that he had more than two children with Susannah.
I have not progressed beyond Sarah Morgan's parents, Thomas Morgan and Nancy Reynolds. Sarah was born in South Carolina and died in St. Clair County, Alabama. She appears to have at least three brothers - Thomas, David and Benjamin - and at least two sisters - Martha and Talitha Jane. Other than that, I have no other information for Sarah.
James was born in South Carolina to John Humphries and Julia Frances Ellis. He had eight brothers - William, Pelham, John, Ellis, Jesse, Berryman, Drury, and William Bryant - and three sisters - Elizabeth, Sarah, and Mary.
His father, John, had married a second time to Mary Jane Clary. This union produced two half-siblings for James - Thompson and Langdon.
I found a short bio about John on Ancestry.com written by a J. C. Coleman Humphries in 1932. He says that John suffered from outbursts of anger citing one such incident whereas he took a shoe knife and carved on his son's arm as punishment.
This might explain why only three granddaughters and his son, Berryman, are the only family members to inherit in his will. Mr. Humphries does mention that John's father's name was William. Some researchers name his mother as Marianne Walker.
Likewise, I do not know anything about Julia Frances Ellis. Some researchers have her father as Benjamin, while one researcher claims that Julia and Mary Clary are one in the same person.
I will have to do more research for this line.
As a side note, it appears that Humphries had originated from Humphreys and Humphrey.
Death Certificate for Telitha, left
Marriage record to Andrew Duke, bottom left
Marriage record to Rodolph Spencer, bottom right